Lizardcube and Dotemu announced today that Streets of Rage 4 is now officially supported on Linux (and macOS), with a port done by Ethan Lee creator of FNA.
Read the full article here: https://www.gamingonlinux.com/2020/11/streets-of-rage-4-is-now-officially-available-for-linux-along-with-vulkan-support-in-fna