Cyrodiil is a dangerous place in The Elder Scrolls IV: Oblivion, and disease can be just as much of a threat as bandits or Daedra. Most diseases are just minor afflictions that sap your stats or cause small debuffs, but the Porphyric Hemophilia is a condition that can ruin your day, literally, because it turns you into a vampire...
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How to cure vampirism in Oblivion or become a vampire on purpose for the nighttime buffs
Source: PC Gamer (opens in a new tab)