- Champions do not appear on difficulty 0
- Difficulty 4 adds 1 more champion to each floor
- Difficulty 5 removes 2 upgrade slots instead of raising upgrade prices
- Difficulty 8 turns all enemies into champions
- Champions now drop weapons instead of keys
- Added new modifier - Fragile Weapons & Enemies
- Some upgrades have been renamed and given sprites
- Brawler -> Scissors
- Long Arms -> Super Arm
- Falloff -> Monocle
- Lightweight Bullets -> Small Bullets
- Wave Beam -> Wavy Snake
- Improved achievement menu
Difficulty Adjustments (Early Access 31.0)
Source: Steam Community (opens in a new tab)