There are several dozens of various statuses in the game. Neutral, positive and negative - all of them affect your character in a particular way, so you better keep an eye on those white/green/red icons in the upper left corner of your screen. We’ll talk about all of them.
First of all, there are statuses that primarily affect your character's vitals, so try not to forget your meal and don’t overwork yourself!
If you're interested in staying healthy and recovering fast, you'll want to see the green icons for 'Vivacity' and 'Natural Recovery' at all times.
Keep an eye on the weather, because weather conditions may have an immediate effect on your character. Is it sunny, windy or rainy? You won’t suffer from it at first, but these statuses may soon transform into other, not so pleasant ones.
Aaaaand that’s what happens if you don’t take weather conditions seriously, eat not the best food and wander around Malaria swamps (what a life!). As a result of external influences, you can gain a disease status. There are several types of them with various gradations. Medicine helps prevent a disease and keeps it from progressing. Sleep and some types of food can also help.
There are also positive 'Quality sleep' and 'Health recovery' statuses that appear when your health is being restored.
Take a minute to rest near a fire and get this nice 'By the fire' status. It will give your character full protection from the cold and pests, and helps to recover faster from damp, wind chill, and freezing, as well as to cure the flu.
'Overloaded' and 'Immobilized' statuses keep track of whether you are carrying too much and if you really need those four massive stones in your Inventory right now.
There is “In water’ status that may transform into ‘Drowning’ status if you forget to breathe or stay in the water for too long. There will be other signs like constantly losing stamina points and loud gurgling sounds. You won’t miss it.
‘Dark’ status is pretty self-explanatory. Just light a fire or wait for the morning.
You shouldn’t stay for too long in the territories with these statuses. Better find some other places to idle.
Several types of medicine will give you 'Protection from pests' status to scare away spiders, scorpions and other pests. There are also several powerful potions made of Living Water, which will give you some nice statuses. Not feeling hunger/thirst/fatigue, unlimited stamina, or the ability to see animals through obstacles — if you find one of those bottles, be sure to take it with you, that may come up handy.
Can’t find a dropped item or look for special objects? Don’t forget to level up your Concentration perk and press V key to gain ‘Concentration’ status allowing you to get into a special focused mode with everything interesting marked and highlighted.
Be sure to always keep the track of all current statuses on a separate tab (press ‘C’ key). Along with the list of all current statuses, you can also find the description of each status, its effects and recommendations on removing it, if it's negative (before it’s too late). Stay safe!