New version is live! This should resolve many of the compatibility issues related to OSD:
v5.3.8
Release: 9/17/2015
• Improved OSD compatibility and fixed crashing in some games when OSD is enabled.
• PrecisionX window position will reset to default if last position was out of screen.
• Monitoring dialog will save settings when window is closed.
• Supports OSD Shadow On/Off
• Updates to tooltips