If you're getting random crashes, then please accept my profuse apologies on behalf of Unity. It looks like they had some bugs in their driver code that can cause all sorts of random lockups. (As far as I can tell, Nvidia is unaffected)
There's 3 options you've got right now!
- Hope AMD fix their issue
- Try using the -force-d3d9 launch option
- Wait for Patch 15
You also have the option of trying out the nightly test build, or just... not playing. Or buying an Nvidia card. 6 options!
I've moved to Unity 5.5 for Patch 15, which has improved things across the board, and, quite importantly, fixes this crash.
Apologies again!