The Sacrificial Heart is just one of the many random items you'll have to find a use for in Path of Exile 2. Just like the Sun Clan Relic, you need to bring this grisly trophy to a certain location if you want to claim its bounty—which is well worth it considering you'll get two passive skill points for your trouble...
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How to use the Sacrificial Heart in Path of Exile 2
Source: PC Gamer (opens in a new tab)